| Arizona Cardinals | Injury | Status | Expected Return |
| Bryant Horner | Strained Hamstring | Questionable | Unknown |
| Jesse Hamaoka | High Ankle Sprain | Out | 12 Weeks |
| Abel Lewis | Broken Arm | Out | 4 Weeks |
| Isaiah Hutton | MCL Damage to the Knee | Out | 4 Weeks |
| Norman Buchanan | Sprained Knee | Questionable | 2 Weeks |
| Jamaal Hodges | Strained Achilles Tendon | Probable | 1 Week |
| Atlanta Falcons | Injury | Status | Expected Return |
| Marcus Cooley | Concussion | Out (in concussion protocol) | 8 Weeks |
| Mason Klaff | Dislocated Shoulder | Doubtful | 3 Weeks |
| Clifton Elliott | Strained Calf Muscle | Out | 3 Weeks |
| Damon Dibble | Pulled Groin | Doubtful | 3 Weeks |
| Grant Washington | Broken Ankle | Out | 3 Weeks |
| Norman Jefferies | Bruised Ribcage | Probable | 2 Weeks |
| Ernie Lyle | Torn Lateral Knee Ligament | Probable | 1 Week |
| Charles McGill | Concussion | Out (in concussion protocol) | 1 Week |
| Tucker Zimmerman | None | 100% |
|
| Baltimore Ravens | Injury | Status | Expected Return |
| Jaylen Mayes | Strained Hamstring | Questionable | Unknown |
| Fred Lugar | Separated Shoulder | Out | 5 Weeks |
| Ernie Gerhardt | ACL Damage to the Knee | Questionable | 3 Weeks |
| Lorenzo Bensen | Pulled Groin | Questionable | 2 Weeks |
| Roderick Tomich | Concussion | Out (in concussion protocol) | 2 Weeks |
| Buffalo Bills | Injury | Status | Expected Return |
| Devin Liles | Turf Toe | Doubtful | Unknown |
| Doug Givens | Broken Ribs | Out | 4 Weeks |
| Dixon Lane | Pulled Groin | Doubtful | 4 Weeks |
| Nicholas McIntyre | Pulled Groin | Questionable | 2 Weeks |
| Brayden Rzentkowski | Torn Knee Cartilage | Questionable | 2 Weeks |
| O.J. Van Dam | Pulled Groin | Probable | 1 Week |
| Matt King | Sprained Thumb | Probable | 1 Week |
| Nick Hartwig | None | 100% |
|
| Tanner Lewis | None | 100% |
|
| Sky Dog Nixon | None | 100% |
|
| Carolina Panthers | Injury | Status | Expected Return |
| Toby Arnold | Reconstructive Knee Surgery | Out | 39 Weeks |
| Moe Siglar | ACL Damage to the Knee | Out | 14 Weeks |
| Ashton Richmond | Severe Hamstring Pull | Out | 8 Weeks |
| Sammie Coles | Concussion | Out (in concussion protocol) | 2 Weeks |
| Zachary Bauer | Hyperextended Elbow | Probable | 1 Week |
| Jackie Colton | Hyperextended Knee | Probable | 1 Week |
| Karl Babbitt | None | 100% |
|
| Chicago Bears | Injury | Status | Expected Return |
| Aiden Perreault | Strained Hamstring | Questionable | Unknown |
| Carter Duncan | Concussion | Out (in concussion protocol) | 9 Weeks |
| Dusty Fulton | Sprained Lateral Knee Ligament | Probable | 4 Weeks |
| Roberto Presley | Sprained Neck | Probable | 2 Weeks |
| Alexander Hardy | Bad Cold | Probable | 1 Week |
| Cincinnati Bengals | Injury | Status | Expected Return |
| Kyle Zardiackas | Strained Hamstring | Questionable | Unknown |
| Fernando Meadows | Concussion | Out (in concussion protocol) | 7 Weeks |
| Claude Gavalas | Broken Arm | Out | 6 Weeks |
| Andy Cobb | Broken Toe | Questionable | 3 Weeks |
| Karl Satterlee | Bruised Ribcage | Probable | 2 Weeks |
| Leo Heap | Knee Tendinitis | Probable | 2 Weeks |
| Roberto Foreman | Sprained Neck | Probable | 2 Weeks |
| Christopher Parker | None | 100% |
|
| Leon Thurman | None | 100% |
|
| Cleveland Browns | Injury | Status | Expected Return |
| Randal Woodson | Strained Hamstring | Questionable | Unknown |
| Cameron Fulcher | Strained Hamstring | Questionable | Unknown |
| Benjamin Eickholt | ACL Knee Surgery | Out | 54 Weeks |
| Lorenzo Newman | Stress Fracture in the Leg | Doubtful | 5 Weeks |
| Douglas Carlisle | Viral Infection | Questionable | 2 Weeks |
| Blake Malone | Broken Arm | Doubtful | 2 Weeks |
| Wesley Lane | High Ankle Sprain | Probable | 1 Week |
| Larry Tyler | Bruised Ribcage | Probable | 1 Week |
| Rod Young | Broken Arm | Probable | 1 Week |
| Ronald Avdic | Shoulder Tendinitis | Probable | 1 Week |
| Joe Kennedy | Knee Bursitis | Probable | 1 Week |
| Riddick Lane | Strained Calf Muscle | Probable | 1 Week |
| Daniel Griggs | None | 100% |
|
| Robert Hulten | None | 100% |
|
| Roberto Mitchell | None | 100% |
|
| Ian Brian | None | 100% |
|
| Bert Marsolais | None | 100% |
|
| Dallas Cowboys | Injury | Status | Expected Return |
| Jay Ozols | Strained Hamstring | Questionable | Unknown |
| Vernon Carlson | Strained Hamstring | Questionable | Unknown |
| Erick Humes | ACL Knee Surgery | Out | 45 Weeks |
| Abel Jarvis | Strained Elbow Tendon | Out | 7 Weeks |
| Jamal Logan | Separated Shoulder | Out | 2 Weeks |
| Marc Davidson | Sprained Lateral Knee Ligament | Probable | 1 Week |
| Ryan Fichialos | Broken Nose | Probable | 1 Week |
| Denver Broncos | Injury | Status | Expected Return |
| Andrew Carlisle | Severe Depression | Out | Unknown |
| Terrance Jasso | Torn Lateral Knee Ligament | Out | 17 Weeks |
| Nate Granados | Severe Hamstring Pull | Out | 9 Weeks |
| Gustavo Wonders | Broken Foot | Questionable | 4 Weeks |
| Ty Nicoloro | Shoulder Tendinitis | Probable | 3 Weeks |
| Nicholas Petitgout | Sprained Knee | Questionable | 2 Weeks |
| Nathan Bronson | Strained Triceps Muscle | Probable | 2 Weeks |
| Steve Collier | None | 100% |
|
| Kaden Summerfield | None | 100% |
|
| Gus Kelly | None | 100% |
|
| Detroit Lions | Injury | Status | Expected Return |
| Shannon Ottis | ACL Damage to the Knee | Out | 11 Weeks |
| Danny Patterson | Broken Clavicle | Out | 5 Weeks |
| Dan Hudson | Strained Patellar Tendon | Doubtful | 4 Weeks |
| Javier Bronson | Strained Back | Out | 3 Weeks |
| Broderick Bates | Strained Adductor Muscle | Questionable | 3 Weeks |
| Hugh Lane | Hyperextended Knee | Questionable | 2 Weeks |
| Kirk Bunning | Strained Patellar Tendon | Probable | 1 Week |
| Sammy Alcott | Hyperextended Elbow | Probable | 1 Week |
| Ernie Lemus | None | 100% |
|
| J.J. Marsh | None | 100% |
|
| Green Bay Packers | Injury | Status | Expected Return |
| Russell Jordan | MCL Knee Surgery | Out | 19 Weeks |
| Kris Hamilton | Bruised Sternum | Probable | 4 Weeks |
| Mitchell Baskerville | Severe Hamstring Pull | Probable | 2 Weeks |
| Byron Schulz | Bad Cold | Probable | 1 Week |
| Marvin Giancursio | Strained Deltoid Muscle | Probable | 1 Week |
| Billy Hayes | None | 100% |
|
| Hayden Conley | None | 100% |
|
| Houston Texans | Injury | Status | Expected Return |
| Brendan Stevenson | Deep Thigh Bruise | Probable | 2 Weeks |
| Kurt Fitzgerald | Hyperextended Knee | Questionable | 2 Weeks |
| Chester Gaines | Bruised Ribcage | Probable | 1 Week |
| Eddie Berner | None | 100% |
|
| Indianapolis Colts | Injury | Status | Expected Return |
| Giovanni Steil | Strained Hamstring | Questionable | Unknown |
| Kody Freeman | Turf Toe | Doubtful | Unknown |
| J.R. Binkow | Ruptured Elbow Tendon | Out | 43 Weeks |
| Taylor Newhouse | High Ankle Sprain | Out | 7 Weeks |
| Alex Hamilton | Strained Elbow Tendon | Out | 6 Weeks |
| Ted Perry | Pulled Groin | Doubtful | 4 Weeks |
| Oscar Joyner | Deep Thigh Bruise | Questionable | 3 Weeks |
| Nate Muller | Broken Toe | Probable | 2 Weeks |
| Elliot Altman | Sprained Thumb | Probable | 2 Weeks |
| Rob Kubus | Knee Tendinitis | Probable | 1 Week |
| Jacksonville Jaguars | Injury | Status | Expected Return |
| Emmanuel Frederick | High Ankle Sprain | Out | 14 Weeks |
| Geoff Fox | Severe Hamstring Pull | Out | 12 Weeks |
| Marco Chapman | Broken Foot | Questionable | 5 Weeks |
| Richard Henning | Knee Tendinitis | Probable | 4 Weeks |
| Thomas Talley | Strained Patellar Tendon | Out | 4 Weeks |
| Alejandro Kulaga | Strained Triceps Muscle | Questionable | 3 Weeks |
| Casey Schulz | Strained Quadriceps Muscle | Probable | 2 Weeks |
| Derrick Leisure | Broken Nose | Probable | 1 Week |
| Earnest Shea | None | 100% |
|
| Chandler Grant | None | 100% |
|
| Billy Austin | None | 100% |
|
| Kansas City Chiefs | Injury | Status | Expected Return |
| Gregory Eppright | Strained Hamstring | Questionable | Unknown |
| Josiah Bush | ACL Knee Surgery | Out | 28 Weeks |
| Kent Landis | Sprained Lateral Knee Ligament | Questionable | 9 Weeks |
| Brody Hirshberg | Sprained Knee | Questionable | 4 Weeks |
| Silas Braham | Pulled Calf Muscle | Out | 4 Weeks |
| Bennett Strickland | Sprained Ankle | Probable | 1 Week |
| Geoff Gray | Pulled Calf Muscle | Questionable | 1 Week |
| Erick Wolfsmith | Sprained Knee | Probable | 1 Week |
| Los Angeles Rams | Injury | Status | Expected Return |
| Spencer Spezzano | Pulled Groin | Doubtful | 3 Weeks |
| Shaun Brooks | Separated Shoulder | Probable | 1 Week |
| Roberto Hines | None | 100% |
|
| Miami Dolphins | Injury | Status | Expected Return |
| J.R. Talley | Torn Ankle Ligament | Out | 19 Weeks |
| Devon Gallardo | Concussion | Out (in concussion protocol) | 10 Weeks |
| Marcos Waeltz | Strained Achilles Tendon | Out | 3 Weeks |
| Louie Ahmad | Strained Elbow Tendon | Out | 3 Weeks |
| Ramon Mathews | Bruised Sternum | Probable | 2 Weeks |
| Mitchell Robert | Knee Tendinitis | Probable | 2 Weeks |
| Antoine Becker | Broken Nose | Probable | 2 Weeks |
| Kaden West | Sprained Ankle | Probable | 1 Week |
| Minnesota Vikings | Injury | Status | Expected Return |
| Arnold Barnhart Jr. | Sprained Neck | Probable | 2 Weeks |
| Cesar Monroe | Knee Tendinitis | Probable | 1 Week |
| Grant Harner | None | 100% |
|
| Robert Rodgers | None | 100% |
|
| Gary Small | None | 100% |
|
| Phil Sell | None | 100% |
|
| Jeffrey Tate | None | 100% |
|
| New England Patriots | Injury | Status | Expected Return |
| Ellis Roberts | Ruptured Adductor Muscle | Out | 20 Weeks |
| Dan O'Donnell | ACL Damage to the Knee | Out | 15 Weeks |
| Dexter Alexander | Torn Rotator Cuff | Out | 10 Weeks |
| Kai Burroughs | Back Surgery | Out | 8 Weeks |
| Eli Mathis | Knee Bursitis | Questionable | 2 Weeks |
| Micah Mang | Pulled Quadriceps Muscle | Doubtful | 2 Weeks |
| Nolan Reuber | Severe Headaches | Doubtful | 2 Weeks |
| T.J. Wells | Sprained Ankle | Probable | 1 Week |
| Jeffrey Sutter | Sprained Knee | Probable | 1 Week |
| Norm Giles | Knee Tendinitis | Probable | 1 Week |
| Tevin Sampson | Broken Finger | Probable | 1 Week |
| Joey Stuvaints | None | 100% |
|
| New Jersey Jets | Injury | Status | Expected Return |
| Jamal Ramsey | Turf Toe | Doubtful | Unknown |
| Tony Johns | Strained Hamstring | Questionable | Unknown |
| Jon Burks | Pulled Calf Muscle | Probable | 1 Week |
| Wes Keyser | Sprained Knee | Probable | 1 Week |
| Eddie Anderson | None | 100% |
|
| New Orleans Saints | Injury | Status | Expected Return |
| Jesse Heath | High Ankle Sprain | Out | 6 Weeks |
| Marquis Sweeney | Bruised Sternum | Probable | 4 Weeks |
| Sammy Carswell | Torn Wrist Tendon | Out | 3 Weeks |
| Shaquille LeTourneau | Broken Finger | Probable | 1 Week |
| J.R. Franklin | Strained Elbow Tendon | Probable | 1 Week |
| Devon Davidson | Separated Shoulder | Probable | 1 Week |
| Gene Godfrey | Sprained Ankle | Probable | 1 Week |
| Theodore Maese | None | 100% |
|
| New York Giants | Injury | Status | Expected Return |
| No Injured Players |
| Oakland Raiders | Injury | Status | Expected Return |
| Rickey Chatham | Strained Hamstring | Questionable | Unknown |
| Drake Kudlacz | Repetitive Concussion Syndrome | Out | 90 Weeks |
| Christian Sipes | Abdominal Strain | Doubtful | 3 Weeks |
| Leonard Irwin | Broken Foot | Probable | 2 Weeks |
| Chuck Shepherd | Bruised Ribcage | Probable | 2 Weeks |
| Antoine Conley | Shin Splints | Probable | 1 Week |
| Heath Somogyi | None | 100% |
|
| Gilbert McElroy | None | 100% |
|
| Philadelphia Eagles | Injury | Status | Expected Return |
| Isaac Martin | Strained Calf Muscle | Out | 4 Weeks |
| Todd Hernandez | Bruised Heel | Probable | 1 Week |
| Phillip Fayo | Concussion | Out (in concussion protocol) | 1 Week |
| Myles Sutter | None | 100% |
|
| Pittsburgh Steelers | Injury | Status | Expected Return |
| Carson Fulcher | Strained Foot Ligament | Out | 4 Weeks |
| Ricardo Price | Hyperextended Elbow | Probable | 1 Week |
| Cedric Robbins | Strained Elbow Tendon | Probable | 1 Week |
| Kelly Stephens | None | 100% |
|
| Kennedy Hampton | None | 100% |
|
| San Diego Chargers | Injury | Status | Expected Return |
| David Logan | Severe Depression | Out | Unknown |
| Jermaine Bush | Ruptured Elbow Tendon | Out | 36 Weeks |
| Asher Perez | Compound Leg Fracture | Out | 29 Weeks |
| Roberto Gamble | MCL Damage to the Knee | Out | 6 Weeks |
| Howard Shipp | Strained Foot Ligament | Out | 3 Weeks |
| Ivan Melnick | Strained Foot Ligament | Probable | 2 Weeks |
| Corbin Palmer | Knee Tendinitis | Probable | 2 Weeks |
| Bradley Hill | Pulled Groin | Questionable | 2 Weeks |
| Archie Crane | Abdominal Strain | Questionable | 2 Weeks |
| Will Fox | Hyperextended Knee | Questionable | 2 Weeks |
| Nicholas Van Pelt | Broken Foot | Probable | 1 Week |
| Courtney Lluellyn | Sprained Knee | Probable | 1 Week |
| Johnnie Roeder | None | 100% |
|
| San Francisco 49ers | Injury | Status | Expected Return |
| Avery Schindler | Turf Toe | Doubtful | Unknown |
| Billy Gill | ACL Knee Surgery | Out | 8 Weeks |
| Sam Salinger | Hyperextended Elbow | Out | 3 Weeks |
| Abraham Hummel | Sprained Knee | Probable | 1 Week |
| Carlton Chapman | Concussion | Out (in concussion protocol) | 1 Week |
| Tanner Daugherty | Knee Contusion | Probable | 1 Week |
| Devonte Woods | None | 100% |
|
| Seattle Seahawks | Injury | Status | Expected Return |
| Neil Durham | Turf Toe | Doubtful | Unknown |
| Marco Manning | Torn Lateral Knee Ligament | Out | 8 Weeks |
| B.J. Brookes | Stress Fracture in the Leg | Doubtful | 3 Weeks |
| Riley Quinteros | Hyperextended Knee | Out | 3 Weeks |
| Winston Marsh | Strained Triceps Muscle | Questionable | 3 Weeks |
| Cooper Coles | Sprained Knee | Questionable | 3 Weeks |
| Jared Delgado | Sprained Ankle | Questionable | 1 Week |
| Randy Mason | Knee Contusion | Probable | 1 Week |
| Jackson Shields | None | 100% |
|
| Cesar O'Neal | None | 100% |
|
| Bruce Akroyd | None | 100% |
|
| Charles Blackwell | None | 100% |
|
| Tampa Bay Buccaneers | Injury | Status | Expected Return |
| Micah Paige | ACL Damage to the Knee | Out | 20 Weeks |
| Hugh Salley | Concussion | Out (in concussion protocol) | 8 Weeks |
| Cary Walsh | Sprained Knee | Questionable | 4 Weeks |
| Spencer Brentlinger | Strained Quadriceps Muscle | Probable | 3 Weeks |
| Louie Schlabaugh | Broken Toe | Probable | 1 Week |
| Tennessee Titans | Injury | Status | Expected Return |
| Larry Chapman | High Ankle Sprain | Out | 19 Weeks |
| Jerald Harada | Strained Elbow Tendon | Out | 6 Weeks |
| Amari Robinson | Knee Tendinitis | Probable | 5 Weeks |
| Donny Zaragoza | Sprained Knee | Questionable | 3 Weeks |
| Irving Tucker | Torn Rotator Cuff | Probable | 2 Weeks |
| Washington Commanders | Injury | Status | Expected Return |
| Eli Randle | Bruised Sternum | Probable | 2 Weeks |
| Arturo Kanu | Broken Finger | Probable | 1 Week |
| Brody Forbes | Elbow Contusion | Probable | 1 Week |
| Everett Spradlin | Shoulder Tendinitis | Probable | 1 Week |